Research Overview

The long-term research programme of the laboratory has been focused on studying the structure-function relationships of microtubule proteins and their interactions with other cytoskeletal elements in cells under normal and pathological conditions. The organization of dynamic microtubule networks is controlled by microtubule organizing centres (MTOCs). One of the key components of MTOCs is γ-tubulin, which is necessary for nucleation of microtubules. Current work focuses on the understanding of the modulation of microtubule properties by signal transduction molecules, the function of γ-tubulin forms, and molecular and functional characterization of regulators of microtubule nucleation. To address these questions, techniques of molecular biology, biochemistry and immunology are being used, as well as a variety of microscopic techniques, including live cell imaging and quantification of microtubule nucleation and plus end dynamics.

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News and updates

  • 27th Cytoskeletal Club

    14-16 September 2022

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  • Journal of Cellular Physiology (cover)

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  • Life Science Alliance (cover)

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  • Protein Downstream Processing (book chapter)

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  • Basophils and Mast Cells (book chapter)

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  • 26th Cytoskeletal Club

    19-21 May 2019

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  • Advanced Materials (cover)

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  • 33rd Europen Cytoskelatal Forum

    20-24 September, 2018

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  • 8th EMBRN Meeting

    25-27 May, 2017

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  • 25th Cytoskeletal Club

    19-21 April, 2017

    25th Anniversary

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  • 24th Cytoskeletal Club

    18-20 May, 2016

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  • Mast Cells (book chapter)

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  • 23rd Cytoskeletal Club

    20-22 May, 2015

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  • Basophils and Mast Cells (book chapter)

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  • 22nd Cytoskeletal Club

    21-23 May, 2014

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  • Deciphering New Molecular Mechanisms of Mast Cell Activation (book chapter)

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  • Protein Downstream Processing (book chapter)

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  • 21st Cytoskeletal Club

    15-17 May, 2013

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  • COST-Action BM1007, Mast Cells and Basophils

    19-20 May, 2012

  • 20th Cytoskeletal Club

    16-18 May, 2012

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  • The Cytoskeleton and Human Disease (book chapter)

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  • Journal of Neuropathology and Experimental Neurology (cover)

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  • Journal of Cellular Physiology (cover)

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  • Plant Cell (cover)

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  • Plant Cell (cover)

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  • Application of Optical Engineering to the Study of Cellular Pathology (book chapter)

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  • Analytical Use of Fluorescent Probes (book Chapters)

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Welcome to Pavel Dráber Lab
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